by MyH Editorial Team | Sep 1, 2025 | Red Blood Cells
Key Takeaways Diamond-Blackfan Anemia or DBA is a rare, congenital blood disorder where the bone marrow fails to produce red blood cells. It is also known as congenital hypoplastic anemia. Causes ▾: The core cause is a defect in ribosome biogenesis, primarily...
by MyH Editorial Team | Aug 26, 2025 | White Blood Cells
Key Takeaways Diffuse large B-cell lymphoma (DLBCL) is the most common and aggressive type of non-Hodgkin lymphoma, a fast-growing cancer of B-lymphocytes. Epidemiology ▾: It is the most common non-Hodgkin lymphoma worldwide, with incidence increasing with age....
by MyH Editorial Team | Aug 17, 2025 | White Blood Cells
Key Takeaways Mantle cell lymphoma (MCL disease) is a rare and aggressive type of non-Hodgkin’s lymphoma that originates from B-cells in the “mantle zone” of the lymph nodes. Pathogenesis ▾: The hallmark of MCL is a specific genetic mutation...
by MyH Editorial Team | Aug 15, 2025 | Hemostasis Disorders
Key Takeaways Factor V Leiden thrombophilia is a genetic condition caused by a mutation in the F5 gene that results in a defective Factor V protein, making it resistant to inactivation by activated protein C (APC). Pathophysiology ▾: Because the mutated Factor...
by MyH Editorial Team | Aug 13, 2025 | Red Blood Cells
Key Takeaways Methemoglobinemia is a blood disorder where the iron in hemoglobin is oxidized from its normal ferrous state (Fe2+) to the ferric state (Fe3+). This abnormal hemoglobin, called methemoglobin (MetHb), can’t carry oxygen. Pathophysiology ▾: It...
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