by MH Team | May 13, 2024 | Platelet Disorders
TL;DR Dengue Virus and Transmission ▾ Dengue is a viral infection spread by mosquitoes, particularly Aedes mosquitoes. There are four serotypes of the dengue virus, and infection with one serotype provides only temporary immunity to that specific type. Clinical...
by MH Team | May 1, 2024 | Red Blood Cells
TL;DR Detailed Clinical History ▾ Explore presenting illness (symptoms, onset, duration, severity). Investigate menstrual history (regularity, bleeding amount) for women. Review past medical, surgical, and drug history. Assess social history (occupation, travel,...
by MH Team | Apr 23, 2024 | Red Blood Cells
TL;DR Hereditary hemochromatosis is a genetic disorder affecting iron metabolism, leading to excessive iron absorption from the diet. It is the most common genetic disease in populations of Northern European descent. Causes ▾ Primarily caused by mutations in the HFE...
by MH Team | Apr 19, 2024 | Lab Protocols, White Blood Cells
Introduction The discovery of the JAK2 V617F mutation revolutionized our understanding of myeloproliferative neoplasms (MPNs). This single nucleotide change, where a guanine (G) is replaced by a thymine (T) at position 1849 in exon 14 of the JAK2 gene, leads to...
by MH Team | Apr 10, 2024 | Red Blood Cells
TL;DR Sideroblastic anemia is a type of anemia characterized by abnormal iron metabolism within red blood cell precursors. Refractory anemia is defined by the presence of many pathological ring sideroblasts in the bone marrow. Causes ▾ Inherited: Mutations in genes...
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