Acute Lymphoblastic Leukemia or ALL

Acute Lymphoblastic Leukemia or ALL

TL;DR Acute Lymphoblastic Leukemia (ALL) is a rapidly progressing malignancy of immature lymphoid cells (lymphoblasts) in the bone marrow. Acute lymphoblastic leukemia (ALL) is primarily classified by WHO as B-ALL (∼80% of cases) or T-ALL...
Delayed Hemolytic Transfusion Reaction

Delayed Hemolytic Transfusion Reaction

TL;DR A Delayed Hemolytic Transfusion Reaction (DHTR) is an immune-mediated adverse event that occurs as a consequence of a blood transfusion. Its defining characteristic is the delayed onset, with signs and symptoms typically appearing 3 to 30 days post-transfusion....
Microangiopathic Hemolytic Anemia (MAHA)

Microangiopathic Hemolytic Anemia (MAHA)

TL;DR Microangiopathic hemolytic anemia or MAHA is a syndrome defined by a triad of microangiopathic damage, hemolytic anemia, and thrombocytopenia, all resulting from the physical fragmentation of red blood cells in small blood vessels. Pathophysiology ▾: The...
Pancytopenia

Pancytopenia

TL;DR Pancytopenia is the reduction of all three major blood cell lines: red blood cells (anemia), white blood cells (leukopenia), and platelets (thrombocytopenia). It is a clinical finding, not a disease itself, indicating an underlying issue. Causes ▾ : The...
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