Heparin-Induced Thrombocytopenia

Heparin-Induced Thrombocytopenia

TL;DR Heparin-induced thrombocytopenia is an immune-mediated reaction to heparin that causes thrombocytopenia and an increased risk of thrombosis. Types ▾: Type I: Non-immune, transient, mild thrombocytopenia. Type II: Immune-mediated, potentially serious, associated...
Thrombophilia

Thrombophilia

TL;DR Thrombophilia is an abnormal predisposition to thrombosis (blood clotting) due to abnormalities in the coagulation system. Inherited Causes ▾: Factor V Leiden, Prothrombin gene mutation, deficiencies of Antithrombin, Protein C, or Protein S. Acquired Causes ▾:...
Catastrophic Antiphospholipid Syndrome

Catastrophic Antiphospholipid Syndrome

TL;DR Catastrophic Antiphospholipid Syndrome (CAPS) is a rare but life-threatening variant of Antiphospholipid Syndrome (APS). It’s thought to arise from a combination of existing APS (aPL), a precipitating event (like infection or surgery), and an amplifying...
Antiphospholipid Syndrome

Antiphospholipid Syndrome

TL;DR Antiphospholipid syndrome is an autoimmune disorder where the body’s immune system mistakenly attacks its own cells, specifically phospholipids, which are important for blood clotting. This can lead to blood clots and pregnancy problems.   Types ▾:...