Vitamin B12 keeps the red cells & nerves healthy, but deficiency can lead to fatigue, numbness, and weakness. Early diagnosis is key to prevent complications.
Red Blood Cells
Systemic Approach to Anemia
Systematic anemia diagnosis starts with a detailed history, exam & blood tests. Iron studies, B12/folate levels & other tests pinpoint the cause (iron deficiency, vitamin deficiency, etc.) leading to targeted treatment & improved outcomes.
Hereditary Hemochromatosis
Hereditary hemochromatosis, an inherited disorder, disrupts iron absorption leading to excessive iron buildup in organs like the liver, heart, and pancreas. Early diagnosis through blood tests is crucial to prevent potential complications like cirrhosis, heart failure, and diabetes. Treatment focuses on iron reduction through phlebotomy and may prevent severe health consequences.
Folate Deficiency
Folate deficiency, a lack of vitamin B9, can lead to fatigue, weakness, and even birth defects.
Pernicious Anemia
Pernicious anemia, an autoimmune condition, disrupts vitamin B12 absorption. This leads to fatigue, nerve problems, and a special type of anemia. Early diagnosis and B12 replacement therapy are key for good health.
Vitamin B12 Deficiency Anemia
Vitamin B12 keeps the red cells & nerves healthy, but deficiency can lead to fatigue, numbness, and weakness. Early diagnosis is key to prevent complications.
Drug-Induced Immune Hemolytic Anemia (DIIHA)
Drug-induced immune hemolytic anemia (DIIHA) challenges diagnostic workup due to diverse mechanisms (hapten model most common). Consider DIIHA in hemolytic anemia with recent medication initiation & positive DAT.
Autoimmune Hemolytic Anemia (AIHA)
AIHA: When your own immune system attacks healthy red blood cells, causing anemia. Treatment aims to suppress this immune response
Hemolytic Anemia
Hemolytic anemia occurs when red blood cells are destroyed faster than they’re produced, leading to fatigue, weakness, and shortness of breath.
Agarose Gel Electrophoresis Preparation for PCR
Agarose gel electrophoresis: where we separate and visualize amplified DNA fragments.
Sickle Cell Test
This test unmasks sickle cells: crescent shadows under the microscope, revealing HbS’s hidden grip on red blood cells.
Hemolysate Preparation for Hb Electrophoresis or Alkaline Denaturation Tests
Red blood cells lysed to release hemoglobin for Hb electrophoresis and alkaline denaturation test. Hemolysate preparation requires careful steps to ensure accuracy and reliability of results.
