ACD (anemia of chronic disease) occurs when inflammation disrupts iron use for red blood cells, causing anemia despite iron stores.
Red Blood Cell Inclusion Bodies
Red blood cell inclusions are hidden clues! These structures in RBCs signal underlying issues. Learn how they help diagnose anemia & other blood disorders.
Red Blood Cell (RBC) Morphology
Red blood cell (RBC) shapes and sizes offer clues to health! Normal RBCs are round and disc-shaped, but abnormal shapes like sickle or teardrop forms can indicate underlying conditions like anemia. Let’s explore what these variations mean!
Differential Diagnosis of Hypochromic Anemia
Hypochromic anemia, marked by pale, small red blood cells, has various causes beyond iron deficiency. A proper diagnosis is crucial for effective treatment. Ruling out conditions like thalassemia or lead poisoning ensures targeted therapy.
Anemia of Chronic Disease (ACD)
ACD (anemia of chronic disease) occurs when inflammation disrupts iron use for red blood cells, causing anemia despite iron stores.
Red Blood Cell (RBC) Morphology
Red blood cell (RBC) shapes and sizes offer clues to health! Normal RBCs are round and disc-shaped, but abnormal shapes like sickle or teardrop forms can indicate underlying conditions like anemia. Let’s explore what these variations mean!
Agarose Gel Electrophoresis Preparation for PCR
Agarose gel electrophoresis: where we separate and visualize amplified DNA fragments.
Hb S Sickling Test
This test unmasks sickle cells: crescent shadows under the microscope, revealing HbS’s hidden grip on red blood cells.
Hemolysate Preparation for Hb Electrophoresis or Alkaline Denaturation Tests
Red blood cells lysed to release hemoglobin for Hb electrophoresis and alkaline denaturation test. Hemolysate preparation requires careful steps to ensure accuracy and reliability of results.
Alpha-Thalassemia: An Imbalanced Problem
Alpha thalassemia is an inherited blood disorder that causes less alpha globin production, leading to less hemoglobin formation thus resulting in anemia.
High Performance Liquid Chromatography (HPLC) for Identification of Hemoglobin Subtypes
HPLC for hemoglobin subtype identification separates and quantifies different hemoglobin variants based on their unique chromatographic properties.
Glucose-6-Phosphate Dehydrogenase (G6PD) Fluorescent Spot Test
The G6PD fluorescent spot test is a rapid and simple screening method for G6PD deficiency that utilizes the enzyme’s ability to reduce NADP+ to NADPH.