Lab Protocols

Bone Marrow Aspiration and Trephine Biopsy

An overview of bone marrow aspiration and trephine biopsy. This guide covers key indications, procedural best practices, and modern result interpretation.

Wright Stain for Peripheral Blood Smear

Learn the Wright stain principle, step-by-step protocol, interpretation and troubleshooting tips in this guide for peripheral blood smears.

Coagulation Screening Panel Interpretation (Coagulation Panel)

A coagulation screening panel is a vital diagnostic tool. It assesses blood clotting (hemostasis) via PT, aPTT, & platelet count, revealing bleeding or clotting risks.

Incubate patient serum with panel RBCs, check for agglutination! Enzymes & antiglobulin tests may be used to reveal hidden antibody reactions.

An image of a bottle containing Brilliant Cresyl Blue (BCB) stain

Supravital Stain: BCB or NMB

Lab Protocols, Red Blood Cells

BCB or new methylene blue (NMB) stains are also known as supravital stains. These stains are commonly used to stain reticulocytes, Heinz bodies or H inclusions

Zone of morphology of a peripheral blood smear is where a peripheral blood should be viewed for morphological abnormalities of the blood cells

Preparation of Peripheral Blood Smears

Lab Protocols, Red Blood Cells

A drop of blood spread on a slide, reveals morphological abnormalities of the blood cells that can be viewed under the microscope.

EDTA blood collection for CBC with differential

CBC with Differential and Other Reference Ranges

Lab Protocols, Red Blood Cells

Reference ranges like complete blood count (CBC) with differential are important because they provide a baseline for interpreting laboratory test results.