White Blood Cells

Mast Cell Activation Syndrome (MCAS)

Explore the biology, symptoms, and modern management of Mast Cell Activation Syndrome (MCAS)

Mast Cell

Learn about mast cell biology, from morphology and development to clinical disorders. An essential guide to diagnosis and lab investigations.

Systemic Mastocytosis

Explore Systemic Mastocytosis: An overview of KIT D816V mutations, WHO diagnostic criteria, and modern management

Image depicting a peripheral blood smear of chronic myeloid leukemia (CML), showcasing leukocytosis with immature granulocytes, basophilia, and eosinophilia

Chronic Myeloid Leukemia or CML

Chronic myeloid leukemia (CML) is a cancer of the blood cells that begins in the bone marrow. It is caused by a genetic abnormality that results in the production of too many white blood cells.

Image depicting a peripheral blood smear showcasing the hallmark findings of CLL

Chronic Lymphocytic Leukemia (CLL)

Chronic lymphocytic leukemia (CLL) is a type of cancer that affects white blood cells called B lymphocytes. In CLL, B lymphocytes become abnormal and grow uncontrollably. This can lead to fatigue, swollen lymph nodes, and easy bruising or bleeding. CLL is a slowly progressing cancer affecting mainly the elderly

Peripheral blood smear showing numerous nucleated red blood cells and dysplastic myeloblasts. (M6 AML).

Acute Leukemia: An Overview

At the heart of acute leukemia lies a disruption of the genetic blueprint, the DNA that carries the instructions for building and maintaining healthy cells. When these instructions become corrupted, through mutations or deletions, the normal development and function of blood cells are derailed.

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