Hemolytic anemia occurs when red blood cells are destroyed faster than they’re produced, leading to fatigue, weakness, and shortness of breath.
Red Blood Cells
Agarose Gel Electrophoresis Preparation for PCR
Agarose gel electrophoresis: where we separate and visualize amplified DNA fragments.
Sickle Cell Test
This test unmasks sickle cells: crescent shadows under the microscope, revealing HbS’s hidden grip on red blood cells.
Differential Diagnosis of Microcytic Hypochromic Anemia
Hypochromic anemia, marked by pale, small red blood cells, has various causes beyond iron deficiency. A proper diagnosis is crucial for effective treatment. Ruling out conditions like thalassemia or lead poisoning ensures targeted therapy.
Anemia of Chronic Disease (ACD)
ACD (anemia of chronic disease) occurs when inflammation disrupts iron use for red blood cells, causing anemia despite iron stores.
Sideroblastic Anemia
Sideroblastic anemia disrupts iron use in red blood cells. Caused by genetic mutations or factors like alcohol abuse, it’s diagnosed by analyzing bone marrow for ring sideroblasts, iron-laden structures.
Beta Thalassemia
Beta thalassemia is a blood disorder caused by a mutation in the gene that produces beta globin, a protein that helps red blood cells carry oxygen. People with beta thalassemia may have mild to severe anemia, and may need blood transfusions and other treatments.
Hereditary Spherocytosis
Hereditary spherocytosis (HS) is a blood disorder that causes red blood cells to be sphere-shaped and less flexible. This makes them more likely to break down, leading to anemia.
