Red Blood Cells

Microangiopathic Hemolytic Anemia (MAHA)

Microangiopathic hemolytic anemia (MAHA) is a syndrome where red cells are sheared in small vessels, causing anemia and low platelets. Key feature: schistocytes.

Pancytopenia

Pancytopenia is a condition where a person has a low count of all three types of blood cells: red, white, and platelets.

Shwachman-Diamond Syndrome (SDS)

Shwachman-Diamond Syndrome: A rare genetic disorder causing pancreatic insufficiency, neutropenia, and skeletal abnormalities.

Paroxysmal Cold Hemoglobinuria

Paroxysmal cold hemoglobinuria (PCH) is a rare autoimmune anemia. Cold exposure triggers red cell destruction, causing dark urine, back pain, and chills. Diagnosis relies on the Donath-Landsteiner test.

Evans Syndrome

Evans Syndrome

Evans syndrome: Rare autoimmune disorder causing low red blood cells & platelets (AIHA & ITP). Can lead to fatigue, bruising, and bleeding.

Pernicious Anemia

Pernicious Anemia

Pernicious anemia, an autoimmune condition, disrupts vitamin B12 absorption. This leads to fatigue, nerve problems, and a special type of anemia. Early diagnosis and B12 replacement therapy are key for good health.

Systemic Approach to Anemia

Systemic Approach to Anemia

Systematic anemia diagnosis starts with a detailed history, exam & blood tests. Iron studies, B12/folate levels & other tests pinpoint the cause (iron deficiency, vitamin deficiency, etc.) leading to targeted treatment & improved outcomes.

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