The spleen: A key organ for immunity and blood filtration. Learn about its function, location, and related health issues.
Red Blood Cells
Erythropoietin
Erythropoietin (EPO) is a hormone that stimulates red blood cell production. It plays a crucial role in oxygen transport and is used to treat anemia in various conditions like kidney disease and cancer.
Fanconi Anemia
Fanconi anemia, a rare genetic disorder, causes bone marrow failure and increases cancer risk. Learn about symptoms, causes, diagnosis, and treatment options.
Paroxysmal Nocturnal Hemoglobinuria (PNH)
Paroxysmal nocturnal hemoglobinuria (PNH): An acquired blood disease where the immune system attacks red cells due to a mutation in the X chromosome.
Warm Autoimmune Hemolytic Anemia (warm AIHA)
Warm AIHA: Immune system attacks red blood cells, causing anemia. Symptoms include fatigue, pallor, and jaundice. Treatment targets immune suppression.
Wilson’s Disease
Wilson’s disease: A rare genetic disorder causing toxic copper buildup in the liver and brain. Early diagnosis and lifelong treatment are crucial.
Red Blood Cells (RBCs): An Overview
Red blood cells are biconcave disc-shaped cells that transport oxygen from the lungs to other parts of the body.
Conventional PCR Protocol for Beta Thalassemia Downstream Sequencing
The beta globin gene PCR protocol for sequencing involves amplifying the beta globin gene using specific primers, followed by Sanger sequencing to determine the DNA sequence.
Aplastic Anemia (AA): A Bone Marrow Failure
Aplastic Anemia, a rare and serious bone marrow failure syndrome, causes pancytopenia, where all the blood cell lineages are suppressed.
Erythrocyte Sedimentation Rate or ESR
ESR measures the sedimentation rate or the length red blood cells fall in a vertical tube over a period of time.
Supravital Stain: BCB or NMB
BCB or new methylene blue (NMB) stains are also known as supravital stains. These stains are commonly used to stain reticulocytes, Heinz bodies or H inclusions
Preparation of Peripheral Blood Smears
A drop of blood spread on a slide, reveals morphological abnormalities of the blood cells that can be viewed under the microscope.