Sideroblastic anemia disrupts iron use in red blood cells. Caused by genetic mutations or factors like alcohol abuse, it’s diagnosed by analyzing bone marrow for ring sideroblasts, iron-laden structures.
Differential Diagnosis of Macrocytic Anemias
Macrocytosis, larger-than-normal red blood cells, can be a sign of vitamin B12 or folate deficiency, liver disease, or bone marrow issues. Early diagnosis is key for targeted treatment.
Differential Diagnosis of Microcytic Hypochromic Anemia
Hypochromic anemia, marked by pale, small red blood cells, has various causes beyond iron deficiency. A proper diagnosis is crucial for effective treatment. Ruling out conditions like thalassemia or lead poisoning ensures targeted therapy.

Thalassemia
Thalassemia is an inherited blood disorder causing reduced hemoglobin production. Symptoms include fatigue, weakness, and jaundice. Treatment involves blood transfusions, iron chelation, and bone marrow transplants.

Severe Malarial Anemia
Malaria, a mosquito-borne illness, can cause severe anemia (low red blood cells) leading to weakness & fatigue. While most malaria cases are mild, severe anemia requires prompt medical attention.

Spleen
The spleen: A key organ for immunity and blood filtration. Learn about its function, location, and related health issues.
Hereditary Spherocytosis
Hereditary spherocytosis (HS) is a blood disorder that causes red blood cells to be sphere-shaped and less flexible. This makes them more likely to break down, leading to anemia.