Sideroblastic anemia disrupts iron use in red blood cells. Caused by genetic mutations or factors like alcohol abuse, it’s diagnosed by analyzing bone marrow for ring sideroblasts, iron-laden structures.
Red Blood Cells
Differential Diagnosis of Macrocytic Anemias
Macrocytosis, larger-than-normal red blood cells, can be a sign of vitamin B12 or folate deficiency, liver disease, or bone marrow issues. Early diagnosis is key for targeted treatment.
Differential Diagnosis of Microcytic Hypochromic Anemia
Hypochromic anemia, marked by pale, small red blood cells, has various causes beyond iron deficiency. A proper diagnosis is crucial for effective treatment. Ruling out conditions like thalassemia or lead poisoning ensures targeted therapy.
Pernicious Anemia
Pernicious anemia, an autoimmune condition, disrupts vitamin B12 absorption. This leads to fatigue, nerve problems, and a special type of anemia. Early diagnosis and B12 replacement therapy are key for good health.
Vitamin B12 Deficiency Anemia
Vitamin B12 keeps the red cells & nerves healthy, but deficiency can lead to fatigue, numbness, and weakness. Early diagnosis is key to prevent complications.
Pernicious Anemia
Pernicious anemia, an autoimmune condition, disrupts vitamin B12 absorption. This leads to fatigue, nerve problems, and a special type of anemia. Early diagnosis and B12 replacement therapy are key for good health.
Anemia: Types, Symptoms & Treatment
Anemia is a condition characterized by a deficiency in red blood cells or hemoglobin below the physiological need of the body.
Red Blood Cells (RBCs): An Overview
Red blood cells are biconcave disc-shaped cells that transport oxygen from the lungs to other parts of the body.
Conventional PCR Protocol for Downstream Sequencing in Beta Thalassemia Diagnosis
The beta globin gene PCR protocol for sequencing involves amplifying the beta globin gene using specific primers, followed by Sanger sequencing to determine the DNA sequence.
Aplastic Anemia (AA): A Bone Marrow Failure
Aplastic Anemia, a rare and serious bone marrow failure syndrome, causes pancytopenia, where all the blood cell lineages are suppressed.
Erythrocyte sedimentation rate (ESR)
ESR measures the sedimentation rate or the length red blood cells fall in a vertical tube over a period of time.
Brilliant Cresyl Blue (BCB) Stain (Methylene Blue)
BCB or new methylene blue (NMB) stains are also known as supravital stains. These stains are commonly used to stain reticulocytes, Heinz bodies or H inclusions
