Systematic anemia diagnosis starts with a detailed history, exam & blood tests. Iron studies, B12/folate levels & other tests pinpoint the cause (iron deficiency, vitamin deficiency, etc.) leading to targeted treatment & improved outcomes.
Red Blood Cells
Hereditary Hemochromatosis
Hereditary hemochromatosis, an inherited disorder, disrupts iron absorption leading to excessive iron buildup in organs like the liver, heart, and pancreas. Early diagnosis through blood tests is crucial to prevent potential complications like cirrhosis, heart failure, and diabetes. Treatment focuses on iron reduction through phlebotomy and may prevent severe health consequences.
Sideroblastic Anemia
Sideroblastic anemia disrupts iron use in red blood cells. Caused by genetic mutations or factors like alcohol abuse, it’s diagnosed by analyzing bone marrow for ring sideroblasts, iron-laden structures.
Interpretation of Iron Studies (Iron Profile)
Iron studies reveal iron deficiency, overload, and other conditions. Learn how MCV, ferritin, and other markers help decipher iron status and guide treatment.
Folate Deficiency
Folate deficiency, a lack of vitamin B9, can lead to fatigue, weakness, and even birth defects.
Interpretation of Iron Studies (Iron Profile)
Iron studies reveal iron deficiency, overload, and other conditions. Learn how MCV, ferritin, and other markers help decipher iron status and guide treatment.
High Performance Liquid Chromatography (HPLC) for Identification of Hemoglobin Subtypes
HPLC for hemoglobin subtype identification separates and quantifies different hemoglobin variants based on their unique chromatographic properties.
Glucose-6-Phosphate Dehydrogenase (G6PD) Fluorescent Spot Test
The G6PD fluorescent spot test is a rapid and simple screening method for G6PD deficiency that utilizes the enzyme’s ability to reduce NADP+ to NADPH.
Anemia: Types, Symptoms & Treatment
Anemia is a condition characterized by a deficiency in red blood cells or hemoglobin below the physiological need of the body.
Red Blood Cells (RBCs): An Overview
Red blood cells are biconcave disc-shaped cells that transport oxygen from the lungs to other parts of the body.
Conventional PCR Protocol for Downstream Sequencing in Beta Thalassemia Diagnosis
The beta globin gene PCR protocol for sequencing involves amplifying the beta globin gene using specific primers, followed by Sanger sequencing to determine the DNA sequence.
Aplastic Anemia (AA): A Bone Marrow Failure
Aplastic Anemia, a rare and serious bone marrow failure syndrome, causes pancytopenia, where all the blood cell lineages are suppressed.
