Folate deficiency, a lack of vitamin B9, can lead to fatigue, weakness, and even birth defects.
Red Blood Cells
Pernicious Anemia
Pernicious anemia, an autoimmune condition, disrupts vitamin B12 absorption. This leads to fatigue, nerve problems, and a special type of anemia. Early diagnosis and B12 replacement therapy are key for good health.
Vitamin B12 Deficiency Anemia
Vitamin B12 keeps the red cells & nerves healthy, but deficiency can lead to fatigue, numbness, and weakness. Early diagnosis is key to prevent complications.
Jaundice (Hyperbilirubinemia)
Jaundice, a condition characterized by yellowing of the skin and eyes, is caused by hyperbilirubinemia, an abnormally high level of bilirubin in the blood. It can be a symptom of various liver or biliary tract diseases.
Thalassemia
Thalassemia is an inherited blood disorder causing reduced hemoglobin production. Symptoms include fatigue, weakness, and jaundice. Treatment involves blood transfusions, iron chelation, and bone marrow transplants.
Neonatal Jaundice (High Bilirubin Levels in Newborns)
Neonatal jaundice is a common condition in newborns causing yellowing of the skin and eyes due to excess bilirubin in the blood. It can be caused by various factors, including immature liver function and certain medical conditions. While often harmless, severe cases can lead to complications.
High Performance Liquid Chromatography (HPLC) for Identification of Hemoglobin Subtypes
HPLC for hemoglobin subtype identification separates and quantifies different hemoglobin variants based on their unique chromatographic properties.
Glucose-6-Phosphate Dehydrogenase (G6PD) Fluorescent Spot Test
The G6PD fluorescent spot test is a rapid and simple screening method for G6PD deficiency that utilizes the enzyme’s ability to reduce NADP+ to NADPH.
Anemia: Types, Symptoms & Treatment
Anemia is a condition characterized by a deficiency in red blood cells or hemoglobin below the physiological need of the body.
Red Blood Cells (RBCs): An Overview
Red blood cells are biconcave disc-shaped cells that transport oxygen from the lungs to other parts of the body.
Conventional PCR Protocol for Downstream Sequencing in Beta Thalassemia Diagnosis
The beta globin gene PCR protocol for sequencing involves amplifying the beta globin gene using specific primers, followed by Sanger sequencing to determine the DNA sequence.
Aplastic Anemia (AA): A Bone Marrow Failure
Aplastic Anemia, a rare and serious bone marrow failure syndrome, causes pancytopenia, where all the blood cell lineages are suppressed.