Sideroblastic anemia disrupts iron use in red blood cells. Caused by genetic mutations or factors like alcohol abuse, it’s diagnosed by analyzing bone marrow for ring sideroblasts, iron-laden structures.
Red Blood Cells
Differential Diagnosis of Macrocytic Anemias
Macrocytosis, larger-than-normal red blood cells, can be a sign of vitamin B12 or folate deficiency, liver disease, or bone marrow issues. Early diagnosis is key for targeted treatment.
Differential Diagnosis of Microcytic Hypochromic Anemia
Hypochromic anemia, marked by pale, small red blood cells, has various causes beyond iron deficiency. A proper diagnosis is crucial for effective treatment. Ruling out conditions like thalassemia or lead poisoning ensures targeted therapy.
Folate Deficiency
Folate deficiency, a lack of vitamin B9, can lead to fatigue, weakness, and even birth defects.
Pernicious Anemia
Pernicious anemia, an autoimmune condition, disrupts vitamin B12 absorption. This leads to fatigue, nerve problems, and a special type of anemia. Early diagnosis and B12 replacement therapy are key for good health.
Interpretation of Iron Studies (Iron Profile)
Iron studies reveal iron deficiency, overload, and other conditions. Learn how MCV, ferritin, and other markers help decipher iron status and guide treatment.
Aplastic Anemia (AA): A Bone Marrow Failure
Aplastic Anemia, a rare and serious bone marrow failure syndrome, causes pancytopenia, where all the blood cell lineages are suppressed.
Erythrocyte sedimentation rate (ESR)
ESR measures the sedimentation rate or the length red blood cells fall in a vertical tube over a period of time.
Brilliant Cresyl Blue (BCB) Stain (Methylene Blue)
BCB or new methylene blue (NMB) stains are also known as supravital stains. These stains are commonly used to stain reticulocytes, Heinz bodies or H inclusions
Preparation of Peripheral Blood Smears
A drop of blood spread on a slide, reveals morphological abnormalities of the blood cells that can be viewed under the microscope.
CBC with Differential and Other Reference Ranges
Reference ranges like complete blood count (CBC) with differential are important because they provide a baseline for interpreting laboratory test results.
Glucose-6-phosphate dehydrogenase (G6PD) deficiency
G6PD deficiency is a common inherited blood disorder that can cause your red blood cells to break down when exposed to certain foods, drugs, or infections.