Vitamin B12 keeps the red cells & nerves healthy, but deficiency can lead to fatigue, numbness, and weakness. Early diagnosis is key to prevent complications.
Red Blood Cells
Systemic Approach to Anemia
Systematic anemia diagnosis starts with a detailed history, exam & blood tests. Iron studies, B12/folate levels & other tests pinpoint the cause (iron deficiency, vitamin deficiency, etc.) leading to targeted treatment & improved outcomes.
Hereditary Hemochromatosis
Hereditary hemochromatosis, an inherited disorder, disrupts iron absorption leading to excessive iron buildup in organs like the liver, heart, and pancreas. Early diagnosis through blood tests is crucial to prevent potential complications like cirrhosis, heart failure, and diabetes. Treatment focuses on iron reduction through phlebotomy and may prevent severe health consequences.
Interpretation of Iron Studies (Iron Profile)
Iron studies reveal iron deficiency, overload, and other conditions. Learn how MCV, ferritin, and other markers help decipher iron status and guide treatment.
Folate Deficiency
Folate deficiency, a lack of vitamin B9, can lead to fatigue, weakness, and even birth defects.
Folate Deficiency
Folate deficiency, a lack of vitamin B9, can lead to fatigue, weakness, and even birth defects.
Agarose Gel Electrophoresis Preparation for PCR
Agarose gel electrophoresis: where we separate and visualize amplified DNA fragments.
Sickle Cell Test
This test unmasks sickle cells: crescent shadows under the microscope, revealing HbS’s hidden grip on red blood cells.
Hemolysate Preparation for Hb Electrophoresis or Alkaline Denaturation Tests
Red blood cells lysed to release hemoglobin for Hb electrophoresis and alkaline denaturation test. Hemolysate preparation requires careful steps to ensure accuracy and reliability of results.
Alpha Thalassemia
Alpha thalassemia is an inherited blood disorder that causes less alpha globin production, leading to less hemoglobin formation thus resulting in anemia.
High Performance Liquid Chromatography (HPLC) for Identification of Hemoglobin Subtypes
HPLC for hemoglobin subtype identification separates and quantifies different hemoglobin variants based on their unique chromatographic properties.
Glucose-6-Phosphate Dehydrogenase (G6PD) Fluorescent Spot Test
The G6PD fluorescent spot test is a rapid and simple screening method for G6PD deficiency that utilizes the enzyme’s ability to reduce NADP+ to NADPH.
