Incubate patient serum with panel RBCs, check for agglutination! Enzymes & antiglobulin tests may be used to reveal hidden antibody reactions.
Transfusion Medicine
Antibody Screening
Antibody screening mixes patient plasma with red blood cells to detect unexpected antibodies. Agglutination indicates possible antibodies, requiring further identification for safe blood transfusions
Serologic Crossmatch
Crossmatching mimics transfusion by mixing recipient serum & donor cells. Clumping (agglutination) indicates incompatibility, preventing transfusion reactions.
Interpretation of Antibody Identification Antigram
Antigen identification antigrams decode antibody reactions in blood transfusions, ensuring safe blood selection by identifying compatible red blood cells that lack the antigen targeted by the recipient’s antibody.
Antibody Identification
Incubate patient serum with panel RBCs, check for agglutination! Enzymes & antiglobulin tests may be used to reveal hidden antibody reactions.
Serologic Crossmatch
Crossmatching mimics transfusion by mixing recipient serum & donor cells. Clumping (agglutination) indicates incompatibility, preventing transfusion reactions.
ABO RhD Test Tube Method
The ABO RhD Blood Grouping Tube Method is a serological technique used to determine an individual’s blood type by mixing blood serum and red blood cells with antisera and observing for agglutination.
ABO Blood Group System
The ABO blood group system is a classification of human blood based on the presence or absence of A and B antigens on red blood cells.
Components of Donated Blood Products
Many different blood components can be derived from donated blood. These components have different functions for different indications. This article gives an overview of the function of the different blood components available.
Acute Hemolytic Transfusion Reaction
Acute hemolytic transfusion reaction (AHTR) is a rare but life-threatening complication of blood transfusion that occurs when the recipient’s immune system attacks the transfused blood cells and destroyed them.
Hemolytic disease of the newborn (Erythroblastosis Fetalis)
Hemolytic disease of the newborn (HDN) is a condition in which a newborn baby’s red blood cells are destroyed. It is caused by incompatibility between the baby’s and mother’s blood types. HDN is preventable and treatable.