Antibody screening mixes patient plasma with red blood cells to detect unexpected antibodies. Agglutination indicates possible antibodies, requiring further identification for safe blood transfusions
Transfusion Medicine
Serologic Crossmatch
Crossmatching mimics transfusion by mixing recipient serum & donor cells. Clumping (agglutination) indicates incompatibility, preventing transfusion reactions.
Indirect Antiglobulin (Coombs) Test (IAT)
Unmask hidden blood threats! IAT protocol detects antibodies in serum, ensuring safe transfusions & diagnosing immune disorders.
Antibody Identification
Incubate patient serum with panel RBCs, check for agglutination! Enzymes & antiglobulin tests may be used to reveal hidden antibody reactions.
Antibody Screening
Antibody screening mixes patient plasma with red blood cells to detect unexpected antibodies. Agglutination indicates possible antibodies, requiring further identification for safe blood transfusions
Indirect Antiglobulin (Coombs) Test (IAT)
Unmask hidden blood threats! IAT protocol detects antibodies in serum, ensuring safe transfusions & diagnosing immune disorders.
ABO Blood Group System
The ABO blood group system is a classification of human blood based on the presence or absence of A and B antigens on red blood cells.
Components of Donated Blood Products
Many different blood components can be derived from donated blood. These components have different functions for different indications. This article gives an overview of the function of the different blood components available.
Acute Hemolytic Transfusion Reaction (ATHR)
Acute hemolytic transfusion reaction (AHTR) is a rare but life-threatening complication of blood transfusion that occurs when the recipient’s immune system attacks the transfused blood cells and destroyed them.
Hemolytic fetal disease of the newborn (HDN)
Hemolytic disease of the newborn (HDN) is a condition in which a newborn baby’s red blood cells are destroyed. It is caused by incompatibility between the baby’s and mother’s blood types. HDN is preventable and treatable.
