tPA is a powerful drug used to dissolve blood clots causing heart attacks, strokes, and pulmonary embolisms. While effective, it also carries risks, primarily bleeding.
Thrombosis: An Overview
Blood clots, called thrombosis, can form in deep veins and travel to the lungs (PE) causing serious complications. While often symptomless, watch for leg swelling, redness, and sudden shortness of breath. Early diagnosis and treatment are crucial to prevent life-threatening risks.
Coagulation (Clotting) Disorders
Coagulation disorders disrupt blood clotting, causing abnormal bleeding or clotting. These can be inherited or acquired later in life due to various factors. Early diagnosis is crucial for proper management.

Catastrophic Antiphospholipid Syndrome
Catastrophic Antiphospholipid Syndrome (CAPS) is a rare, severe autoimmune disease causing rapid-onset, widespread blood clotting and multi-organ failure. Prompt diagnosis and aggressive treatment are crucial for survival.

Antiphospholipid Syndrome
Antiphospholipid syndrome (APS) is an autoimmune disorder that increases the risk of blood clots, pregnancy complications, and other health problems. Early diagnosis and management are crucial.

Thrombophilia
Thrombophilia is an increased tendency to form blood clots. It can be inherited or acquired, raising the risk of DVT, PE, and other thrombotic events. Understanding its causes and management is crucial.
Activated Partial Thromboplastin Time (aPTT) Blood Test
The APTT assay measures how long it takes for a blood clot to form by measuring the amount of time it takes for fibrinogen to be converted to fibrin.
Prothrombin Time (PT) & INR
The PT assay is used to diagnose and monitor a variety of bleeding and clotting disorders by measuring how long it takes a blood clot to form.
Immune Thrombocytopenia (ITP)
Immune thrombocytopenia (ITP) is a rare autoimmune disorder in which the body’s immune system destroys its own platelets.
Disseminated Intravascular Coagulation (DIC)
Disseminated intravascular coagulation (DIC) occurs when the blood coagulation system is overwhelmed causing widespread blood clots and bleeding throughout the body.
Hemophilia
Hemophilia is a rare inherited blood disorder that affects the ability of blood to clot. People with hemophilia often bleed for longer than usual after an injury or surgery.
Hemorrhagic Disease of the Newborn
Hemorrhagic disease of the newborn is a bleeding disorder that occurs in newborns due to a deficiency of vitamin K.