Thrombocytopenia, a condition with a low platelet count, can cause easy bruising and bleeding. While it often has no symptoms, severe cases can lead to internal bleeding. It can arise from various causes, including infections, medications, or autoimmune disorders. Early diagnosis and treatment are crucial to prevent complications.
Platelet Disorders
Vascular Bleeding Disorders
Vascular bleeding disorders come in two forms: inherited (passed down in families) and acquired (developed throughout life due to factors like vitamin deficiencies or medications). Both cause easy bruising & abnormal bleeding.
Dengue & Thrombocytopenia
Dengue isn’t just a fever and rash. This mosquito-borne illness can cause severe complications like bleeding and shock. Early diagnosis is key to preventing these and ensuring a smooth recovery for patients.
Coagulation (Clotting) Disorders
Coagulation disorders disrupt blood clotting, causing abnormal bleeding or clotting. These can be inherited or acquired later in life due to various factors. Early diagnosis is crucial for proper management.
Platelet Function Disorders
Platelet function disorders disrupt blood clotting, causing excessive bleeding. Inherited or acquired, these conditions can range from mild to severe.
Thrombocytopenia
Thrombocytopenia, a condition with a low platelet count, can cause easy bruising and bleeding. While it often has no symptoms, severe cases can lead to internal bleeding. It can arise from various causes, including infections, medications, or autoimmune disorders. Early diagnosis and treatment are crucial to prevent complications.
Platelet Aggregation Test (PAT)
Platelet aggregation test: Checking how blood cells clump to form clots using different agonists.
Physiology of Hemostasis
Hemostasis is the remarkable biological process that keeps our blood flowing within the confines of our vascular network.
Platelet
From their role in wound healing to their potential for causing harm, platelets are a captivating paradox.
Manual APTT Mixing Studies
Manual APTT mixing studies involve mixing patient plasma with normal plasma or specific factor concentrates to differentiate factor deficiencies from inhibitors
Thrombotic thrombocytopenic purpura (TTP)
Thrombotic thrombocytopenic purpura (TTP) is a rare and life-threatening blood disorder that causes blood clots to form throughout the body.
Activated Partial Thromboplastin Time (aPTT) Blood Test
The APTT assay measures how long it takes for a blood clot to form by measuring the amount of time it takes for fibrinogen to be converted to fibrin.
