Smoldering Multiple Myeloma (SMM) is an asymptomatic precursor to MM, defined by high clonal plasma cell burden and M-protein without MDEs. Risk stratification is key.
White Blood Cells
Acute Lymphoblastic Leukemia or ALL
Acute Lymphoblastic Leukemia (ALL) is a cancer of immature white blood cells. Learn its cause, symptoms, and modern treatment, including CAR T-cell therapy.
Chediak-Higashi Syndrome
Chediak-Higashi syndrome (CHS) is a rare genetic disorder characterized by oculocutaneous albinism, immune deficiency, and neurological decline.
Plasma Cell
The plasma cell is the terminal B-lymphocyte, the immune system’s antibody factory for mass Ig secretion, recognized by its eccentric nucleus.
Monoclonal Gammopathy of Undetermined Significance (MGUS)
MGUS is an asymptomatic clonal disorder. It is the precursor to Multiple Myeloma, requiring only active surveillance and risk monitoring.
Smoldering Multiple Myeloma (SMM)
Smoldering Multiple Myeloma (SMM) is an asymptomatic precursor to MM, defined by high clonal plasma cell burden and M-protein without MDEs. Risk stratification is key.
Hypersensitivity Reactions: Causes and Mechanisms
Hypersensitivity is an exaggerated, undesirable immune response to an antigen, causing tissue damage. It encompasses four types: IgE-mediated (allergies), cytotoxic, immune complex, and delayed cell-mediated reactions.
Basophilia (High Basophils)
Basophilia is when basophil count are elevated. It often signals underlying issues like MPNs, allergies, or inflammation.
Lymphopenia or Low Lymphocytes
Lymphopenia is a low lymphocyte count, weakening immunity. It increases infection risk and flags underlying issues like cancer or severe illness.
Monocytosis (High Monocytes)
Monocytosis: Elevated monocytes signal underlying health issues. Learn causes (infections, cancers), symptoms, diagnosis, and management.
Lymphocytosis (High Lymphocytes)
Lymphocytosis: High lymphocyte count. It can be a harmless immune response or signal serious conditions like leukemia.
Leukopenia (Low White Cell Count)
Leukopenia: Low white blood cell count, weakening immunity. Learn about causes, symptoms, diagnosis, and management of this condition.