MGUS is an asymptomatic clonal disorder. It is the precursor to Multiple Myeloma, requiring only active surveillance and risk monitoring.
White Blood Cells
Smoldering Multiple Myeloma (SMM)
Smoldering Multiple Myeloma (SMM) is an asymptomatic precursor to MM, defined by high clonal plasma cell burden and M-protein without MDEs. Risk stratification is key.
Acute Lymphoblastic Leukemia or ALL
Acute Lymphoblastic Leukemia (ALL) is a cancer of immature white blood cells. Learn its cause, symptoms, and modern treatment, including CAR T-cell therapy.
Plasma Cell
The plasma cell is the terminal B-lymphocyte, the immune system’s antibody factory for mass Ig secretion, recognized by its eccentric nucleus.
Monoclonal Gammopathy of Undetermined Significance (MGUS)
MGUS is an asymptomatic clonal disorder. It is the precursor to Multiple Myeloma, requiring only active surveillance and risk monitoring.
Acute Lymphoblastic Leukemia or ALL
Acute Lymphoblastic Leukemia (ALL) is a cancer of immature white blood cells. Learn its cause, symptoms, and modern treatment, including CAR T-cell therapy.
Eosinophilic Asthma
Eosinophilic asthma is a severe subtype of asthma, driven by high eosinophil levels. It often resists standard treatments and may not be allergy-related.
Hypereosinophilic Syndrome (HES)
Hypereosinophilic Syndrome (HES) is a rare disorder causing persistently high eosinophil levels, leading to organ damage and inflammation.
Leukemoid Reaction
Leukemoid reaction is a benign, reactive process with elevated LAP & no Philadelphia chromosome, unlike malignant CML.
Causes of Atypical Lymphocytes (Reactive Lymphocytes)
Atypical lymphocytes are activated immune cells, often seen in infections. Their unique look aids diagnosis, but distinguishing it from cancer is important.
Hypersensitivity Reactions: Causes and Mechanisms
Hypersensitivity is an exaggerated, undesirable immune response to an antigen, causing tissue damage. It encompasses four types: IgE-mediated (allergies), cytotoxic, immune complex, and delayed cell-mediated reactions.
Basophilia (High Basophils)
Basophilia is when basophil count are elevated. It often signals underlying issues like MPNs, allergies, or inflammation.