Hemostasis Disorders | My Hematology

Hemostasis Disorders

Hemophilia C

Discover how Hemophilia C (Factor XI deficiency) differs from types A and B, including its unique symptoms, diagnosis, and modern care.

Hemophilia B

Hemophilia B is a rare, inherited bleeding disorder caused by a lack of Factor IX. Modern treatments now include non-factor and gene therapies

Hemophilia A

Hemophilia A is an X-linked bleeding disorder from a Factor VIII deficiency. It causes deep joint bleeds and is managed by FVIII replacement or gene therapy.

Thrombophilia

Hemostasis Disorders

Catastrophic Antiphospholipid Syndrome

Hemostasis Disorders

Antiphospholipid Syndrome

Hemostasis Disorders

Close-up image of a peripheral blood smear showing thrombocytosis. Numerous red blood cells are visible, along with an abnormally high number of platelets, appearing as small purple dots of various sizes and shapes, distributed throughout the smear. This increased platelet count is characteristic of thrombocytosis, a medical condition where the body produces too many platelets.

Thrombocytosis (High Platelet Count)

Hemostasis Disorders, Platelet Disorders

HELLP Syndrome

HELLP Syndrome

Hemostasis Disorders, Platelet Disorders

Ecchymoses

Ecchymoses

Hemostasis Disorders, Platelet Disorders

Ecchymoses, or bruises, are skin discolorations from blood leakage. Causes range from minor injury to underlying medical issues. Understanding them is key.

Platelet

Platelet

Hemostasis Disorders

From their role in wound healing to their potential for causing harm, platelets are a captivating paradox.

Manual APTT Mixing Study

Manual APTT Mixing Study

Hemostasis Disorders, Lab Protocols

Manual APTT mixing studies involve mixing patient plasma with normal plasma or specific factor concentrates to differentiate factor deficiencies from inhibitors

Thrombotic Thrombocytopenic Purpura (TTP) & ADAMTS13

Thrombotic Thrombocytopenic Purpura (TTP) & ADAMTS13

Hemostasis Disorders

Thrombotic thrombocytopenic purpura (TTP) is a rare and life-threatening blood disorder that causes blood clots to form throughout the body.

Image depicting the activated partial thromboplastin time (aPTT) assay process, highlighting the key steps involved in measuring the intrinsic coagulation pathway

Activated Partial Thromboplastin Time (aPTT) Blood Test

Hemostasis Disorders, Lab Protocols

The APTT assay measures how long it takes for a blood clot to form by measuring the amount of time it takes for fibrinogen to be converted to fibrin.

The coagulation cascade divided into extrinsic and intrinsic pathways where prothrombin time (PT) and activated partial thromboplastin time (aPTT) are involved

Prothrombin Time (PT) & INR

Hemostasis Disorders, Lab Protocols

The PT assay is used to diagnose and monitor a variety of bleeding and clotting disorders by measuring how long it takes a blood clot to form.

Image depicting macrophages engulfing platelets, highlighting the immune-mediated destruction of platelets in immune thrombocytopenic purpura (ITP)

Primary Immune Thrombocytopenia or Primary ITP

Hemostasis Disorders

Immune thrombocytopenia (ITP) is a rare autoimmune disorder in which the body’s immune system destroys its own platelets.