CAR T-cell therapy is a revolutionary cancer treatment using engineered T-cells to target and destroy cancer cells.
White Blood Cells
Macrophage
Macrophages are essential immune cells that engulf and digest foreign particles, playing a crucial role in inflammation and tissue repair. They are found throughout the body and are involved in various diseases, including infections and cancer.
Basophils
Basophils are white blood cells that play a crucial role in allergic reactions and inflammation. They release histamine and other mediators, contributing to symptoms like sneezing, runny nose, and hives. Elevated basophil counts can be associated with certain conditions, such as asthma and chronic myeloid leukemia.
Dendritic Cells
Dendritic cells (DCs) process antigens & present them to T cells, triggering immune responses.
Natural Killer Cells
Natural Killer (NK) cells are vital immune cells that provide rapid defense against infections and cancer. They recognize and eliminate stressed or infected cells without prior sensitization, playing a key role in immunosurveillance.
Waldenström Macroglobulinemia
Waldenström Macroglobulinemia (WM): Rare lymphoma, excess IgM. Causes fatigue, neuropathy, & hyperviscosity. Early diagnosis & tailored treatment are key.
Lymphoma
Lymphoma: Diverse malignancies of lymphocytes. Hodgkin’s & Non-Hodgkin’s subtypes present with swollen nodes, fever, night sweats, fatigue.
Flow Cytometry Immunophenotyping of Blood
Blood cells stained with fluorescent antibodies reveal hidden markers, like a cellular fingerprint. Flow cytometry analyzes millions of cells, painting a detailed picture of immune health, disease clues, and treatment insights.
Immunohistochemistry Staining (IHC)
This immunohistochemistry protocol guides you step-by-step through visualizing specific proteins in tissue sections, aiding in accurate diagnosis of various diseases.
Myelodysplastic Syndromes (MDS): An Overview
MDS is a blood disorder where bone marrow malfunctions, causing abnormal blood cell production. Symptoms like fatigue, shortness of breath, and infections may occur.
Acute Myeloid Leukemia (AML)
Acute myeloid leukemia (AML) is a rapidly progressing and aggressive blood cancer that arises from the uncontrolled growth of myeloid cells in the bone marrow.
Leukocyte/Neutrophil Alkaline Phosphatase (LAP/NAP) Stain
The NAP stain is used to differentiate between granulocytes and agranulocytes based on their naphthol AS-D chloroacetate esterase (NASD-CE) enzyme activity.