Deep vein thrombosis (DVT): Blood clot in leg vein, triggered by slow flow & damage. Can travel to lungs (PE), causing breathing problems & even death.
Platelet Disorders
Fibrinolysis
The process of fibrinolysis dissolves fibrin clots after wound healing, restoring blood flow and preventing unwanted thrombus formation.
Secondary Hemostasis: Coagulation Cascade
Coagulation cascade creates a fibrin mesh that strengthens and stabilizes the platelet plug into a permanent clot.
Thrombocytopenia
Thrombocytopenia, a condition with a low platelet count, can cause easy bruising and bleeding. While it often has no symptoms, severe cases can lead to internal bleeding. It can arise from various causes, including infections, medications, or autoimmune disorders. Early diagnosis and treatment are crucial to prevent complications.
Vascular Bleeding Disorders
Vascular bleeding disorders come in two forms: inherited (passed down in families) and acquired (developed throughout life due to factors like vitamin deficiencies or medications). Both cause easy bruising & abnormal bleeding.
Vascular Bleeding Disorders
Vascular bleeding disorders come in two forms: inherited (passed down in families) and acquired (developed throughout life due to factors like vitamin deficiencies or medications). Both cause easy bruising & abnormal bleeding.
Prothrombin Time (PT) & INR
The PT assay is used to diagnose and monitor a variety of bleeding and clotting disorders by measuring how long it takes a blood clot to form.
Immune Thrombocytopenia (ITP)
Immune thrombocytopenia (ITP) is a rare autoimmune disorder in which the body’s immune system destroys its own platelets.
Disseminated Intravascular Coagulation (DIC)
Disseminated intravascular coagulation (DIC) occurs when the blood coagulation system is overwhelmed causing widespread blood clots and bleeding throughout the body.
Hemophilia
Hemophilia is a rare inherited blood disorder that affects the ability of blood to clot. People with hemophilia often bleed for longer than usual after an injury or surgery.
Vitamin K Deficiency Bleeding (Hemorrhagic Disease of the Newborn)
Hemorrhagic disease of the newborn is a bleeding disorder that occurs in newborns due to a deficiency of vitamin K.
von Willebrand Disorder (vWD)
Von Willebrand disorder (VWD) is a common inherited bleeding disorder caused by a deficiency of von Willebrand factor (vWF), a protein that helps blood clot.
