Hypersensitivity is an exaggerated, undesirable immune response to an antigen, causing tissue damage. It encompasses four types: IgE-mediated (allergies), cytotoxic, immune complex, and delayed cell-mediated reactions.
White Blood Cells
Basophilia (High Basophils)
Basophilia is when basophil count are elevated. It often signals underlying issues like MPNs, allergies, or inflammation.
Lymphopenia or Low Lymphocytes
Lymphopenia is a low lymphocyte count, weakening immunity. It increases infection risk and flags underlying issues like cancer or severe illness.
Eosinophilic Asthma
Eosinophilic asthma is a severe subtype of asthma, driven by high eosinophil levels. It often resists standard treatments and may not be allergy-related.
Hypereosinophilic Syndrome (HES)
Hypereosinophilic Syndrome (HES) is a rare disorder causing persistently high eosinophil levels, leading to organ damage and inflammation.
Eosinophilic Asthma
Eosinophilic asthma is a severe subtype of asthma, driven by high eosinophil levels. It often resists standard treatments and may not be allergy-related.
AL Amyloidosis (Primary Amyloidosis)
AL amyloidosis occurs when misfolded light-chain proteins deposit in organs. Prompt treatment improves outcomes.
Sjögren’s Syndrome
Sjögren’s syndrome: An autoimmune disease causing dry eyes, mouth. Systemic effects is possible. Early diagnosis & management are key.
Waldenström Macroglobulinemia
Waldenström Macroglobulinemia (WM): Rare lymphoma, excess IgM. Causes fatigue, neuropathy, & hyperviscosity. Early diagnosis & tailored treatment are key.
Dendritic Cells
Dendritic cells (DCs) process antigens & present them to T cells, triggering immune responses.
Natural Killer Cells
Natural Killer (NK) cells are vital immune cells that provide rapid defense against infections and cancer. They recognize and eliminate stressed or infected cells without prior sensitization, playing a key role in immunosurveillance.
Burkitt Lymphoma
Burkitt Lymphoma is a rare cancer affecting children and adults. Key symptoms include rapidly growing tumors, often in the jaw or abdomen.