The hemostasis mechanism operates to maintain blood in a fluid state, to arrest bleeding at site of injury through the formation of a haemostatic plug and to ensure removal of the plug when healing is complete. These are achieved through at least five essential elements in haemostasis; blood vessels, platelets, plasma coagulation factors, natural inhibitors and fibrinolytic system. Normal physiology involves a delicate balance of the system to maintain equilibrium as disturbance in any of the elements mentioned, leads to either bleeding or thrombosis within the body.