The ABO blood group system is based on the presence or absence of two antigens, A and B, on the surface of red blood cells. There are four possible ABO blood groups: A, B, AB, and O.
The tube method is a widely used technique for ABO blood group testing. It is a simple, reliable, and cost-effective method that can be performed in most laboratory settings.
HPLC has revolutionized hemoglobin subtype identification, offering a powerful tool for diagnosing and managing hemoglobinopathies. Its high sensitivity, specificity, and ability to quantify different hemoglobin variants make it an invaluable technique in clinical and research settings. As research continues, the application of HPLC in hemoglobinopathy diagnosis and management is likely to expand even further.
The G6PD fluorescent spot test is a rapid and reliable method for diagnosing glucose-6-phosphate dehydrogenase (G6PD) deficiency, a genetic disorder characterized by an enzyme deficiency that can lead to hemolytic anemia. This simple yet effective test relies on the enzyme’s ability to convert nicotinamide adenine dinucleotide phosphate (NADP+) to its fluorescent form, NADPH. The intensity of fluorescence observed under ultraviolet (UV) light directly correlates with G6PD activity.
The ABO blood group system is based on the presence or absence of two antigens, A and B, on the surface of red blood cells. There are four possible ABO blood groups: A, B, AB, and O.
The tube method is a widely used technique for ABO blood group testing. It is a simple, reliable, and cost-effective method that can be performed in most laboratory settings.
HPLC has revolutionized hemoglobin subtype identification, offering a powerful tool for diagnosing and managing hemoglobinopathies. Its high sensitivity, specificity, and ability to quantify different hemoglobin variants make it an invaluable technique in clinical and research settings. As research continues, the application of HPLC in hemoglobinopathy diagnosis and management is likely to expand even further.
The G6PD fluorescent spot test is a rapid and reliable method for diagnosing glucose-6-phosphate dehydrogenase (G6PD) deficiency, a genetic disorder characterized by an enzyme deficiency that can lead to hemolytic anemia. This simple yet effective test relies on the enzyme’s ability to convert nicotinamide adenine dinucleotide phosphate (NADP+) to its fluorescent form, NADPH. The intensity of fluorescence observed under ultraviolet (UV) light directly correlates with G6PD activity.
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